The predicted E2 binding residues of the HsIFT172 U-box domain are depicted in the model ... A mouse monoclonal antibody against acetylated tubulin (Sigma-Aldrich, Clone 6-11B-1, diluted 1:500) was ...

Ubiquitin-binding domains (UBDs) are modular elements that bind non-covalently to the protein modifier ubiquitin. Specific ubiquitin–UBD interactions are crucial for the regulation of multiple ...

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Microtubules are cylindrical polymers composed of alpha and beta tubulin. They are a major component of the cytoskeleton and mediate crucial cellular functions including formation of the mitotic ...

School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, People’s Republic of China ...

Aim: Kidney impairment is observed in patients with COVID-19. The effect of anti-COVID-19 agent remdesivir on kidneys is currently unknown. We aimed to determine the effect of remdesivir on renal ...