Jonathan Thomas, PhD, JD, is President and CEO of the California Institute for Regenerative Medicine (CIRM). Thomas was previously the Chair of the CIRM governing Board from June 2011 to March 2023.

At meetings of the CIRM governing board, patients, clinicians and researchers speak about the hope of stem cell research for a particular disease area. These are their stories.

A major challenge in developing stem cell-based cures for disease is maturing those cells into adult cell types that can be used for transplantation or to study human disease. Dr. Mark Mercola has a ...

Earl J. Beadle Productions, Inc. Stem cells have the potential to treat a wide range of diseases, but developing those cures is a process that has many hurdles. Dr. Hans Keirstead has a CIRM grant to ...

The signaling protein Wnt7a has been implicated in ensuring nerve cells called neurons reach their correct targets and in the formation of synapses between neurons; however studies of the role of ...

Embryonic stem cells have the potential to help treat 70 or more diseases, but developing those new therapies will take time. Alan Lewis is the former president and CEO of Novocell (now ViaCyte), a La ...

维生素 C (VitC) 除了作为一般抗氧化剂的作用外，长期以来一直被认为在高剂量下具有直接的抗癌活性。 VitC通过氧化和表观遗传机制发挥作用，高剂量时可以在体外直接杀死肿瘤细胞并延缓体内 ...

人类一生中存在多种干细胞，并保持其分裂和转变为多种细胞类型的能力。 不同类型的成体干细胞遍布全身，并驻留在特定组织内，作为细胞储备库，可以补充因衰老、疾病、创伤、化疗或电离 ...

病毒感染很常见，对于患有免疫系统疾病的患者来说可能会危及生命。 由于免疫细胞（T 细胞）有助于控制许多病毒感染，因此在先前的研究中，使用病毒特异性 T 细胞（VST）治疗一直是免疫 ...

治疗候选或设备血液干细胞将经过基因工程改造，以保护它们免受胶质母细胞瘤患者化疗的影响，从而提高患者的生存率。 适应症 新诊断的多形性胶质母细胞瘤 (GBM) 或任何新诊断的 IV 级神经 ...

深度烧伤无法产生新血管，会延迟伤口床的构建，增加感染的风险，并导致毁容或形成凸起或增厚的疤痕，也称为肥厚性疤痕。 为了应对这一挑战，我们创建了一种多功能分子，通过连接到名为 ...

解构亨廷顿病 (HD) 等神经退行性疾病的机制基础一直是一项特别具有挑战性的任务，主要依赖于死后组织样本、受影响个体的非神经细胞系和模型生物体。最近发表在《Cell Stem Cell》上的两篇 ...