This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood.

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood.

Objective Patients with increased PD-L1 + host cells in tumours are more potent to benefit from antiprogrammed death-1/programmed death ligand-1 (PD-L1) treatment, but the underlying mechanism is ...

It feels like the Splinter Cell remake has been on its way for a while now, which isn't helped by the fact it's been over three years since we heard anything official about the game. From what we ...

Cell growth usually refers to cell proliferation, the increase in cell numbers that occurs through repeated cell division. Cell growth can also refer to the enlargement of cell volume, which can ...

Cell signalling is the mechanism by which stimuli are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Types of cell signalling pathways ...