This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...

Researchers discover how Zika virus and related viruses replicate in human cells, illuminating potential new vaccines.

Creative Diagnostics, a reagent supplier and developer focused on biologics quality control, has announced the launch of its new Viral Nucleic Acid Residue Assay Kits (qPCR) to ensure the purity and ...

大卫·萨巴蒂尼（David Sabatini），曾因发现对多种细胞过程的调控都至关重要的mTOR激酶而声名显赫的美国顶尖科学家，最近正面临着对其科学成果的严重挑战。 David ...

Their collaboration has resulted in engineered cells called ‘synthetic organizers’ that deliver instructions to stem cells, telling them to grow into specific tissues and organs.

These regulators are known as MYB, HDAC2, and FOXA2 and when they were suppressed in colon cancer cells, the cells switched back to a normal-like state, removing the cancer threat without ...

CS1 plays an important role in the adhesion of myeloma cells to bone marrow stromal cells (27). U266, MM.1S, IM9, Raji, and K562 cells were conserved by our laboratory. HEK-293T cells were purchased ...

THP-1, Daudi and NK-92 cells were purchased from ATCC and HEK 293T cells from Cell Genesys. All cells were maintained at 37°C with 5% CO2. THP-1 cells were cultured in IMDM media (ATCC) supplemented ...

Professor Kwang-Hyun Cho remarked, "The fact that cancer cells can be converted back to normal cells is an astonishing phenomenon. This study proves that such reversion can be systematically induced." ...

A large-scale single-cell study shows aging happens in specific stages driven by molecular cues, offering targets to modify the aging process and revealing key age and sex-related cellular differences ...