Enhances B Cell Responses in Type 2 Inflammation Through IL-17RB Receptor,” published in the January 2025 issue of Allergy ...

B cell receptor (BCR) signaling plays a fundamental role in B cell development, activation, and antibody responses. The BCR consists of a membrane immunoglobulin (mIg), the antigen recognition subunit ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

In summary, these findings show evidence of IFN activation in BM PC from SLE. ANA are found in lupus bone marrow. SLE BM PC express a type I IFN gene signature. BM PC subset distribution was similar ...

In patients with RCC, exceptional response to immunotherapy may be related to clonal neoantigen-driven cytotoxic T-cell ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Dark zone lymphoma includes aggressive B-cell lymphomas with shared molecular features. While some respond to escalated ...

In a report released yesterday, Matthew Biegler from Oppenheimer reiterated a Buy rating on Nurix Therapeutics (NRIX – Research Report), with a ...

Researchers believe the innovative idea holds immense promise for tackling a wide range of diseases including cancer through ...

Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent ...

Background Increased expression of B cell activating factor (BAFF or B lymphocyte stimulator) may explain the B cell activation characteristic of primary Sjögren's syndrome (pSS). Objectives To ...