Of the many cellular functions regulated by signal transduction proteins, one of the most critical is cell-cycle progression. Some cell-cycle regulatory proteins must commit suicide after they ...

Although the cell cycle is a highly integrated process, distinct areas of interest within this field of study have emerged. For instance, many genes and proteins that influence the passage from ...

Protein modifications are key to cell survival because they ensure they do what they are supposed to do in a healthy system.

Proliferating animal cells maintain a stable size distribution over generations despite fluctuations in cell growth and division size. Previously, we showed that cell size control involves both cell ...

Mitosis, the fundamental process by which cells divide, ensures the accurate distribution of genetic material to daughter ...

An exploration of the unanswered questions in how the molecular chaperone Hsp90 supports protein homeostasis, and how single-molecule techniques could drive future breakthroughs in answering them.