Stator assigns multiple states and (sub)types to a single cell using coordinated gene expression and/or non-expression in a ...

This developmental plasticity requires a strict temporal and spatial control of the cell cycle. Cell-cycle activation in quiescent cells is correlated with a change in chromatin structure and ...

EBNALP alters looping factor YY1 DNA binding and 3D genome organization which might facilitate cell cycle progression and prevent cell death. EBNALP is tethered to DNA by DPF2. EBNALP recruits YY1 to ...

DNA’s iconic double helix has long been the symbol of life’s blueprint. However, the human genome conceals far more ...

Their collaboration has resulted in engineered cells called ‘synthetic organizers’ that deliver instructions to stem cells, telling them to grow into specific tissues and organs.

Professor Kwang-Hyun Cho remarked, "The fact that cancer cells can be converted back to normal cells is an astonishing phenomenon. This study proves that such reversion can be systematically induced." ...

A large-scale single-cell study shows aging happens in specific stages driven by molecular cues, offering targets to modify the aging process and revealing key age and sex-related cellular differences ...

MSCs also regulate B cell function by inhibiting proliferation and antibody production, affecting IL-10 production and B cell cycle progression. They interact with innate immune cells, reprogramming ...