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肺炎球菌多糖结合物原液中二甲基亚砜残留量检测方法的建立与验证
目的 建立并验证肺炎球菌多糖结合物原液中二甲基亚砜(dimethyl sulfoxide,DMSO)的检测方法。 方法 通过优化反相高效液相色谱法(reversed phase high performance liquid chromatography,RP-HPLC)中的流动相、柱温以及流速,建立最优检测方法,并对该方法的专属性、线性 ...
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