Revolutionary nasal spray offers hope by potentially delaying Alzheimer's progression through cutting-edge neurological ...

A new study found that stimulating CB2, a receptor involved in immune cell function, improved cognitive performance in Alzheimer's disease (AD) mouse models. Researchers showed that activating CB2 ...

This study presents an important application of high-content image-based morphological profiling to quantitatively and systematically characterize induced pluripotent stem cell-derived mixed neural ...

Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, P. R. China Tang Center for Herbal ...

Microglial dysregulation is a key component of Alzheimer's disease. Butovsky's lab previously designed a way to study how microglia respond to neurodegeneration and confirmed that a specific ...

If the relative contributions of astrocytes and microglia are not properly ... astroglial-enriched cultures is likely to be mainly microglial in origin. This review considers cell culture protocol ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The carboxyl terminus of Hsc70-interacting ...

This study examined whether sex, age, microglial activation or ApoE4 modulates the Aβ to p-tau axis, a critical event in the amyloid cascade that triggers the progression of Alzheimer’s disease (AD) ...

For over a century after their discovery astrocytes were regarded merely as cells located among other brain cells to hold and give support to neurons. Astrocytes activation, “astrocytosis” or A1 ...

Inflammatory responses are closely associated with many neurologic disorders and influence their outcome. In vivo imaging can document events accompanying neuroinflammation, such as changes in blood ...