Purpose: The effects of extreme temperatures on drug delivery of two albuterol sulfate hydrofluoroalkane, metered-dose inhalers (MDIs) were evaluated.Methods. Three Proventil HFA and three ...

Rather similar results were observed in the USA in the ALTA trial (Albuterol for the Treatment of ALI). ALTA was a placebo-controlled multicentre study of nebulized salbutamol in patients with ALI.