TX45 improved both left ventricular function and pulmonary hemodynamics in patients with Group 2 Pulmonary Hypertension in Heart Failure with preserved Ejection Fraction (“PH-HFpEF”), supporting ...

Tectonic Therapeutic said the findings support the design and population for Phase 2 APEX trial, which will test TX45 in ...

Alveolar Capillary Dysplasia (ACD ... leading to severe respiratory issues in newborns. Pulmonary Arterial Hypertension (PAH): A type of high blood pressure that affects the arteries in the ...

Tectonic Therapeutic has done well to advance its Fc-fusion protein candidate TX45 into a phase 2 study targeting patients ...

Tectonic Therapeutic (TECX) announced positive interim data from the Phase 1b acute hemodynamic clinical trial of its lead product candidate, ...

Shares of Tectonic Therapeutic, Inc. (NASDAQ: TECX) surged 40% following the announcement of encouraging interim data from a Phase 1b trial for its TX45 treatment in patients with Group 2 Pulmonary ...

One study indicated that EIPH-positive horses had higher hematocrit values, which may contribute to increased pulmonary capillary pressure, a factor in the development of EIPH[1]. Additionally ...

Tectonic Therapeutic shares doubled, to $56.80, after the company said it saw positive interim data from a Phase 1b acute hemodynamic clinical trial of its lead product candidate, TX45, a long-acting, ...

(Lancet Diabetes & Endocrinology) Among patients with end-stage heart failure and low pulmonary capillary wedge pressure, left ventricular assist device therapy was associated with milder but ...

While pericytes are important regulators of capillary function and homeostasis, the lack of specific markers has hampered the investigation of pericyte biology. This study identifies Higd1b as a ...