Purpose: The pharmacology, spectrum of activity, pharmacokinetics, clinical efficacy, adverse events, dosage and administration, drug interactions, and place in therapy of tigecycline are reviewed.
Changes Clinical Practice: Tigecycline should not be used as monotherapy in patients with ventilator-associated pneumonia (VAP). I found this article very important because it shows that ...
In human beings, there is a ∼16,569 bp circular mitochondrial DNA (mtDNA) encoding 22 tRNAs, 12S and 16S rRNAs, 13 polypeptides that constitute the central core of ETC/OxPhos complexes, and some ...
药品说明书是临床医师开立药物的主要依据。但随着循证医学的日益发展,药物临床试验周期长,药品说明书更新慢等问题使许多药品说明书中的使用适应证、用量及用法远远落后于临床实际应用。药物治疗是抢救重症患者必不可少的重要治疗手段。而重症患者是一个特殊群体,疾病 ...
Human β-defensin 3 (HBD3) and the cathelicidin LL-37 exhibited synergistic effects in combination with tigecycline, moxifloxacin, piperacillin-tazobactam and meropenem, on Clostridium difficile ...
Myroides infections are caused by opportunistic bacteria that are primarily found in the environment. These Gram-negative bacteria, particularly Myroides odoratimimus and Myroides odoratus, are ...
Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands ...