Objectives: To assess the efficacy and tolerability of valsartan and valsartan plus hydrochlorothiazide (HCTZ), given alone or as part of a combination regimen with other antihypertensive agents ...

in patients with heart failure with reduced ejection fraction and patients with heart failure with preserved ejection fraction), PARAGON (sacubitril and valsartan), CHARM (candesartan), TOPCAT and ...