Open and endoscopic carpal-tunnel releases are commonly used as the definitive treatment for carpal tunnel syndrome. This ...

New catheter materials for peripherally inserted central catheters (PICCs) may reduce the risk of device failure due to infectious, thrombotic, and catheter occlusion events. However, data from ...

Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for myelofibrosis. Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation ...

Highly pathogenic avian influenza A(H5N1) viruses have caused widespread infections in dairy cows and poultry in the United States, with sporadic human cases. We describe characteristics of human ...

The continuous emergence and reemergence of tickborne diseases have presented an increasing threat to human health. 1,2 We conducted an active surveillance of febrile patients with recent tick ...

Talquetamab is a T-cell–redirecting bispecific antibody targeting G protein–coupled receptor class C group 5 member D (GPRC5D). 13-15 In the MonumenTAL-1 study, more than 71% of the patients ...

Dr. Annie Liu (Medicine): A 35-year-old woman was admitted to this hospital because of shortness of breath and edema in the legs. Eight weeks before the current presentation, the patient was ...

For over 200 years, the New England Journal of Medicine (NEJM) has brought important medical news to the world’s most influential physicians. The global medical community, physicians, and ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

Panel A shows worldwide age-standardized incidence and mortality rates for cervical cancer in 2022. Data are from the GLOBOCAN database and were collated by the International Agency for Research ...

Multiple diseases in children have been linked to manufactured synthetic chemicals, which are subject to few legal or policy constraints. A revamping of law and restructuring of the chemical ...

In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information by sharing relevant background and ...