Health among the Amish is characterized by higher incidences of particular genetic disorders, especially among the Old Order Amish. These disorders include dwarfism, [1] Angelman syndrome, [2] and various metabolic disorders, such as Tay-Sachs disease, [3] as well as an unusual distribution of blood types. [4]

Because of their closed population stemming from a small number of German immigrants -- about 200 individuals -- the Amish carry unusual concentrations of gene mutations that cause a number of...

Ellis–Van Creveld syndrome often is the result of founder effects in isolated human populations, such as the Amish and some small island inhabitants. Although relatively rare, this disorder does occur with higher incidence within founder-effect populations due to lack of genetic variability.

2024年8月15日 · Amish and Mennonites exhibit certain rare diseases uncommon in other populations. These include: Ellis-van Creveld syndrome (a type of dwarfism) Glutaric aciduria; Crigler-Najjar syndrome; Maple syrup urine disease

Equally bizarre, and also transmitted through a recessive gene, is the new form of dwarfism found by Dr. McKusick among the Amish in more than a dozen communities. It is a new kind of genetic...

Two types of dwarfism occur in the Amish with unusually Ilioh fre- quency. One type, the Ellis-van Crevcld syndrome, is the subject of the discussion that follows. The second type, a newly recoonized disorder which wc shall call cartilaoe-hair hypoplasia (CHI-I), will be the subject of a later presentation (G).

2000年3月1日 · The discovery of the gene that, when mutated, causes a form of dwarfism (Ellis-van Creveld syndrome) has been accelerated through a collaborative effort between geneticists and the Old Order...

Through studies of the Amish in the last year scientists have found “new” (previously undescribed) derangements of health that are hereditary. They have also uncovered relatively large numbers of...

2023年12月27日 · Debunk some common misconceptions about the Amish population. Several recent news stories have questioned the long-held belief that first cousins should not marry due to a higher likelihood of birth defects in their children. However, medical studies clearly show these stories to be spurious.

2024年6月20日 · The Amish community has a higher incidence of specific genetic disorders, leading to an increased occurrence of birth defects. These disorders include dwarfism, Angelman syndrome, various metabolic disorders such as Tay-Sachs disease, and an unusual distribution of …