2023年8月30日 · In this Review, we provide a holistic introduction to the different types of biocide chemistries used in disinfectant and antiseptic products, their applications, mechanisms of action and...

Known mechanisms of microbial resistance (both intrinsic and acquired) to biocides are reviewed, with emphasis on the clinical implications of these reports. Antiseptics and disinfectants are used extensively in hospitals and other health care settings for …

1975年1月1日 · Certain biochemical aspects of mechanism of disinfection are discussed in the paper. The total dehydrogenase activity of intact E. coli cells is affected by chlorine dose and this correlates with per cent survivals. The succinic dehydrogenase activity in the crude extract of E. coli is affected by chlorine within the bactericidal concentrations ...

In this Review, we explore our current understanding of the mechanisms of action of biocides, the bacterial resistance mechanisms encompassing both intrinsic and acquired resistance and the...

1998年1月1日 · Disinfection kinetics offer a measure to differentiate between physiochemical and chemical interactions. Increasingly demanding disinfectant applications require more sophisticated use of biocidal systems.

In-depth knowledge of disinfection and sterilization is a key component of infection control. Sterilization completely removes a spore, whereas disinfection cannot. Disinfectants are classified as oxidants and non-oxidants. The decision regarding which method to apply is based on Spaulding's classification.

The resistance mechanisms for disinfectants resemble those of antibiotics resistance. Generally, these mechanisms reduce the overall concentration of microbicides the organism is exposed to or find a way to evade the compound.

2023年8月30日 · In this Review, we explore our current understanding of the mechanisms of action of biocides, the bacterial resistance mechanisms encompassing both intrinsic and acquired resistance and the influence of bacterial biofilms on resistance. We also consider the impact of bacteria that survive biocide exposure in environmental and clinical contexts.

2025年1月28日 · In general, disinfectants have three mechanisms of action or ways that they affect or kill an organism: Cross-linking, coagulating, clumping; structure and function disruption; and oxidizing. Alcohol Mechanism of action: Cross-linking, coagulating, clumping.

2018年3月1日 · The primary inactivation mechanism of UV disinfection is the damage to microbial nucleic acid by physical processes (e.g., UV light adsorption) that lead to cell replication dysfunction, contributing to the loss of culturability. However, the late change in the cellular membrane occurred at high UV doses, and was observed by SEM and FCM methods ...