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2024年11月8日 · Discover comprehensive details about Tafenoquine, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it. The updated...

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Tafenoquine, sold under the brand name Krintafel among others, is a medication used to prevent and to treat malaria. [3] With respect to acute malaria, it is used together with other medications to prevent relapse by Plasmodium vivax. [3] It may be used to prevent all types of malaria. [3] It is taken by mouth. [4]

2025年1月10日 · ARAKODA tablets contain 100 mg of tafenoquine (equivalent to 125.5 mg of tafenoquine succinate) and are dark pink, film-coated, capsule-shaped, and debossed with ‘TQ100’ on one side. ARAKODA tablets are packed in blister packs or bottles.

Single-dose tafenoquine (TQ), an 8-aminoquinoline, has recently been approved by the U.S. FDA for the treatment of P. vivax malaria along with a blood schizonticidal. TQ is active against all stages of P. vivax lifecycle.

2014年3月22日 · Eligible patients received chloroquine (days 1-3) and were randomly assigned (1:1:1:1:1:1) by a computer-generated randomisation schedule to receive single-dose tafenoquine 50 mg, 100 mg, 300 mg, or 600 mg, primaquine 15 mg for 14 days, or chloroquine alone.

Current treatment of vivax malaria by 3 days of chloroquine and 14 days of low dose of primaquine suffers from poor compliance. The incomplete clearance of vivax reservoir pose a threat to India’s and regional malaria elimination plans. Tafenoquine as an alternative to primaquine may overcome some of the challenges to malaria elimination.

Relapses of Plasmodium vivax malaria threaten disease elimination: time to deploy tafenoquine in India? BMJ Glob Health. 2021 Feb;6 (2):e004558. doi: 10.1136/bmjgh-2020-004558. 1 Parasite and Host Biology, National Institute of Malaria Research, New Delhi, Delhi, India.

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