Glycerol-3-phosphate dehydrogenase (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate (a.k.a. glycerone phosphate, outdated) to sn-glycerol 3-phosphate. [2] Glycerol-3-phosphate dehydrogenase serves as a major link between carbohydrate metabolism and lipid metabolism.

甘油-3-磷酸脱氢酶 (NAD+) （英語： glycerol-3-phosphate dehydrogenase (NAD+)， EC 1.1.1.8 （页面存档备份，存于 互联网档案馆））是一种以 NAD + 或 NADP + 为 受体 、作用于 供体 CH - OH 基团 上的 氧化还原酶。 这种 酶 能 催化 以下 酶促反应： 甘油-3-磷酸脱氢酶 (NAD +)主要参与 甘油磷酸脂 的 代谢 过程。 Boyer, P.D., Lardy, H. and Myrback, K. (Eds.). The Enzymes 7 2nd. New York: Academic Press. 1963: 85–96. Brosemer RW, Kuhn RW.

Sn-glycerol-3-phosphate dehydrogenase (GlpD) is an essential membrane enzyme, functioning at the central junction of respiration, glycolysis, and phospholipid biosynthesis. Its critical role is indicated by the multitiered regulatory mechanisms that …

2025年1月28日 · With a quinone or similar compound as acceptor. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis. In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.

2024年5月1日 · In this review, we summarize and update current knowledge regarding the functions and effects of GPS to provide an overview of how the enzymes influence disease conditions. The potential and...

Glycerol-3-phosphate dehydrogenase is an NAD-dependent oxidoreductase that catalyzes the oxidation of glycerol 3-phosphate to dihydroxyacetone phosphate. Glycerol-3-phosphate dehydrogenase activity was investigated utilizing glycerol-3-phosphate and NAD as substrates and recording in a continuous assay the NADH formation (λ = 340 nm) at 37°C.

Mitochondrial glycerol-3-phosphate dehydrogenase is a flavin-linked respiratory chain dehydrogenase that oxidizes glycerol-3-phosphate (G3P) to dihydroxyacetone phosphate (DAP) (redox potential −190mV) with concurrent reduction of flavin adenine dinucleotide (FAD) to FADH2 and transfers electrons to coenzyme Q (CoQ).

Glycerol-3-phosphate dehydrogenase is an NAD-dependent oxidoreductase that catalyzes the oxidation of glycerol 3-phosphate to dihydroxyacetone phosphate. Glycerol-3-phosphate dehydrogenase activity was investigated utilizing glycerol-3-phosphate and NAD as substrates and recording in a continuous assay the NADH formation (λ = 340 nm) at 37°C.

Human liver glycerol-3-phosphate dehydrogenase (hlGPDH) catalyzes the reduction of dihydroxyacetone phosphate (DHAP) to form glycerol 3-phosphate, using the binding energy associated with the nonreacting phosphodianion of the substrate to properly orient the enzyme-substrate complex within the active site.

2024年12月25日 · This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+.