Benzodiazepine Metabolism Chart Temazepam Nordiazepam Oxazepam Diazepam Conjugation (glucuronidation) Urinary Excretion Alprazolam α hydroxy-aprazolam Triazolam α hydroxy …

Following lorazepam administration (2 mg, p.o.) to 6 volunteers, metabolites were identified in urine by electrospray ionization LC-MS/MS, aided by the use of deuterated analogues …

Lorazepam and its metabolites in blood, urine and faeces were identified by thin-layer and gas chromatography and by mass spectrometry. The principal metabolite in man, dog, pig and cat …

Lorazepam and its metabolites in blood, urine and faeces were identified by thin-layer and gas chromatography and by mass spectrometry. The principal metabolite in man, dog, pig and cat …

Lorazepam is metabolized in the liver by conjugation into inactive lorazepam-glucuronide. This metabolism does not involve liver oxidation, so is relatively unaffected by reduced liver …

CYP2C19 and CYP3A4 are the major players in the metabolism of benzodiazepines that undergo phase I metabolism (figure 1). Phase I metabolism tends to be reduced in the elderly, along …

1976年10月1日 · Lorazepam and its metabolites in blood, urine and faeces were identified by thin-layer and gas chromatography and by mass spectrometry. The principal metabolite in man, …

2024年5月25日 · Metabolism: Lorazepam undergoes conjugation in the liver and experiences enterohepatic recirculation. Lorazepam glucuronide is an inactive metabolite. The medication …

2011年2月20日 · Following lorazepam administration (2 mg, p.o.) to 6 volunteers, metabolites were identified in urine by electrospray ionization LC-MS/MS, aided by the use of deuterated …

Lorazepam and its metabolites in blood, urine and faeces were identified by thin-layer and gas chromatography and by mass spectrometry. The principal metabolite in man, dog, pig and cat …