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Molecular Cell aims to publish the best research in molecular biology. The journal covers core cellular processes. Molecular Cell is particularly interested in papers that answer longstanding questions, open new avenues of research, report unexpected findings, or change the way we think about biological processes. More
Issue: Molecular Cell
In this issue of Molecular Cell, studies by Xu et al., Kimble et al. and Elango et al., examine how yeast and mammalian cells process DNA double-strand breaks that arise when the DNA replication machinery encounters a DNA nick.
New articles: Molecular Cell
4 天之前 · Shen et al. reveal that TBP, via recruiting chromatin remodeler EP400 and increasing local chromatin accessibility, achieves mitotic retention on Drosophila neural stem cell (NSC) chromosomes. TBP acts as a crucial mitotic bookmarker to preserve NSC self-renewal fate memory in neural development.
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Molecular Cell publishes 24 issues per year and releases new articles online each week. Our editorial team consists of PhD-trained editors who work closely with authors, reviewers, and the scientific editorial board to maintain the journal’s high standards and to bring exciting new discoveries to readers.
Issue: Molecular Cell
2024年12月19日 · In this issue of Molecular Cell, Sun et al. reveal that the long non-coding RNA (lncRNA) DNAJC3-AS1 plays a dual role in maintaining the rRNA processing function of fibrillarin (FBL) in cancer cells. It promotes FBL condensation while preventing abnormal aggregation, offering new therapeutic insights for cancer treatment by targeting lncRNAs ...
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The editors of Molecular Cell hope that reviewers will prepare their reviews using a template that we have developed in consultation with scientists. For more information, please see our review guidelines and template.
Issue: Molecular Cell
2024年10月3日 · This issue of Molecular Cell explores the many faces of RNA, diving into the fundamental processes mediating the life cycle of RNA, the regulatory roles of RNA in cellular processes, the importance of RNA in disease, and the technologies used to study RNA.
Three-step mechanism of promoter escape by RNA polymerase II
2024年4月10日 · However, the exact molecular mechanism by which TFIIF is removed from RNA Pol II remains elusive. The mechanism of TFIIE and TFIIH release from RNA Pol II is also unclear.
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Molecular Cell aims to publish the best in molecular biology and beyond. In addition to fundamental cellular processes, we are interested in papers that show how molecular biology can be used to go beyond basic mechanisms to discover new biology, understand diseases, and to create new tools.
RNA-driven phase transitions in biomolecular condensates - Cell …
2024年10月3日 · Although RNAs are core components of many cellular condensates, the underlying molecular determinants for the formation, regulation, and function of ribonucleoprotein condensates have largely been studied from a protein-centric perspective.