Prephenic acid, commonly also known by its anionic form prephenate, is an intermediate in the biosynthesis of the aromatic amino acids phenylalanine and tyrosine, as well as of a large number of secondary metabolites of the shikimate pathway.

预苯酸 （英語： Prephenic acid）是 莽草酸途径 的一种中间体，用于芳香族 氨基酸 （仅 苯丙氨酸 和 酪氨酸，色氨酸的合成不经过预苯酸）以及许多 次生代谢产物 的 生物合成。 预苯酸的生物合成由 分支酸 通过 [3,3]- σ 克莱森重排 生成。

Prephenic acid is an oxo dicarboxylic acid that consists of 4-hydroxycyclohexa-2,5-diene-1-carboxylic acid substituted by a 2-carboxy-2-oxoethyl group at position 1. It has a role as a plant metabolite and an Escherichia coli metabolite. It is a conjugate acid of a prephenate (2-) and a (1s,4s)-prephenate (2-).

2011年3月6日 · 预苯酸盐，或称： (1-羧基-4-羟-2,5-环己二烯基)代丙酮酸盐。 为生物合成芳香族氨基酸（苯丙氨酸，酪胺酸）的中间体.

2010年9月23日 · Prephenate is the direct precursor of phenylpyruvate and 4-hydroxyphenylpyruvate in the biogenesis of phenylalanine and tyrosine by action of the decarboxylative, aromatizing enzymes prephenate deh...

2010年11月21日 · Biochemical and genetic characterization of enzymes showed that PPA-AT directs carbon flux from prephenate toward arogenate, making the arogenate pathway predominant in plant phenylalanine ...

2013年11月25日 · In the first (the arogenate pathway), a shared transamination reaction catalysed by prephenate aminotransferase (PPA-AT), produces L -arogenate, which can then either be dehydrated/decarboxylated...

2014年7月28日 · Through phylogenetic, bioinformatic, and biochemical analyses of prephenate aminotransferase enzymes from deep taxonomic lineages, this study revealed unique evolutionary history and molecular changes of key enzymes responsible for phenylalanine biosynthesis in plants.

2021年10月14日 · Prephenate(2-) | C10H8O6-2 | CID 5460303 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

2010年10月26日 · Prephenate is the direct precursor of phenylpyruvate and 4-hydroxyphenylpyruvate in the biogenesis of phenylalanine and tyrosine by action of the decarboxylative, aromatizing enzymes prephenate dehydratase and dehydrogenase, respectively. The recent characterization of BacA in bacilysin biosynthesis …