Vemurafenib (INN), sold under the brand name Zelboraf, is a medication used for the treatment of late-stage melanoma. [2] . It is an inhibitor of the B-Raf enzyme and was developed by Plexxikon. [2] Vemurafenib causes programmed cell death in melanoma cell lines. [3] .

2024年3月15日 · What is vemurafenib? Vemurafenib is used to treat melanoma (skin cancer) that has spread to other parts of the body or cannot be removed by surgery. Vemurafenib is also used to treat Erdheim-Chester Disease (a rare blood cancer). Vemurafenib is used only if your cancer has a specific genetic marker (an abnormal "BRAF" gene).

2023年8月28日 · Vemurafenib is the first BRAF inhibitor that is used to treat advanced malignant melanoma. Early results show that it may prolong life for several months, but the drug is also prohibitively expensive and has several severe adverse effects.

Vemurafenib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread of cancer cells.

Vemurafenib is a kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.

Vemurafenib is approved to treat patients whose cancer has a certain mutation in the BRAF gene, including: Erdheim-Chester disease. Melanoma that cannot be removed by surgery or has spread to other parts of the body. Vemurafenib is also being studied in …

Vemurafenib is used to treat a type of skin cancer (melanoma). It is also used to treat a rare type of blood cell cancer called Erdheim-Chester disease. These cancer cells have a certain type...

Vemurafenib is used to treat melanoma (a type of skin cancer) that has spread or that cannot be removed by surgery. It is only used if the melanoma cells have the BRAF V600E mutation. Your doctor will use a special test to look for this mutation.

VEMURAFENIB (Vem ue RAF e nib) is a medicine that targets proteins in cancer cells and stops the cancer cells from growing. It is used to treat melanoma, a type of skin cancer, and Erdheim-Chester disease.

2024年4月22日 · Zelboraf (vemurafenib) is used to treat skin cancer (metastatic melanoma). Includes Zelboraf side effects, interactions and indications.