2024年12月6日 · The research collaboration will leverage Muna’s MiND-MAP platform, which analyzes analyze post-mortem brain samples from people with Alzheimer’s and compares them with the brains of healthy individuals, centenarians with and without cognitive impairment, and people without cognitive decline despite age or exposure to risk factors.. This approach is designed to help uncover the genetic and ...

2024年9月26日 · The board’s findings were announced by therapy developer Cassava Sciences, which said in a press release that the company expects to share data from one clinical trial later this year, and from the other by the middle of next year.. The two trials, dubbed RETHINK-ALZ (NCT04994483) and REFOCUS-ALZ (NCT05026177), have collectively enrolled 1,929 people with mild to moderate Alzheimer’s.

2024年7月11日 · Most patients who took foralumab nasal spray for at least six months as part of an expanded use program for nonactive secondary progressive MS saw a reduction in microglia activity in the brain. Patients also reported less fatigue, a common symptom of MS. “Given that nasal foralumab dampens microglial inflammation in subjects with advanced progressive MS and microglial activation is a ...

2024年10月31日 · To help advocates get the word out, the AFA has prepared resources including an Alzheimer’s fact sheet and tips for healthy aging.The foundation also is offering images that can be used as cover photos to tell the world about going teal for Alzheimer’s awareness and loving someone with Alzheimer’s.. Alzheimer’s disease is a neurological condition marked by problems with memory and ...

2017年9月18日 · The team used the data to create a global model of molecular links to the parasite-infected human brain. They used systems biology to determine the mechanisms through which a T. gondii infection can cause disease.Systems biology involves using computers to create mathematical models of complex biological systems.

2021年1月25日 · The device uses gamma frequency technology — called GENUS, for gamma entrainment using sensory stimuli — as a way to stimulate the brain in a non-invasive way.This can be done as an auditory (via sound) or visual (via light) stimulation. In mouse models of Alzheimer’s disease, researchers had already observed that, prior to the onset of cognitive decline, the brain showed a pattern of ...

2024年11月8日 · The modified dosing regimen reduced ARIA-E the most in patients with two copies of the ApoE4 gene variant, which is known to have a high genetic risk for Alzheimer’s. With the modification, 19% of these patients experienced ARIA-E compared with 57% on the standard dosing regimen, lowering their relative risk by 67%, according to Eli Lilly.

2024年2月8日 · Two Phase 3 clinical trials are testing the effectiveness of simufilam, an experimental oral therapy that’s designed to improve cognition in people with Alzheimer’s disease.. Top-line results from the RETHINK-ALZ trial (NCT04994483) are expected by the end of this year, according to simufilam’s developer Cassava Sciences.Results from the second study, REFOCUS-ALZ study (NCT05026177), are ...

2024年3月14日 · The test, Simoa p-Tau 217, has the potential to help doctors diagnose Alzheimer’s in people with cognitive decline before the patients show outward signs of the disease. Alzheimer’s begins with the buildup of proteins, which can be detected via imaging tests before symptoms such as memory loss and disorientation appear. “Early detection is crucial in shaping effective care strategies and ...

2022年5月24日 · “In the care home, I really wanted Jelly Drops to tackle dehydration and also to be really fun and engaging and sort of a social tool in the care home as well,” Hornby said in a video interview with Alzheimer’s News Today.. Hornby created the forerunner to Jelly Drops for his master’s graduation project at Imperial College …