Editorial: Why DNA sequencing is an effective tool for patient care
2019年4月23日 · In 2012, Mayo Clinic adopted DNA sequencing as a major tool in individualized medicine by using targeted gene panels and whole exome sequencing. We started by looking for actionable targets in patients with advanced cancers (unique features of a tumor that can make one therapeutic drug particularly effective).
Science Saturday: A big step forward, bringing DNA sequencing …
2023年4月8日 · Their comprehensive DNA test uses Next Generation Sequencing technology to screen the exome for genetic variants that can significantly increase the risk for disease. It reads all 20,000 genes that code for proteins, plus hundreds of thousands of regions outside the protein-coding regions known to be informative and have the most effect on a ...
Mayo Clinic scientist explains genome sequencing of SARS-CoV-2
2021年12月9日 · This is next-generation sequencing — the process of sequencing DNA or RNA by producing millions of sequence reads in a massively parallel manner. Also known as deep sequencing, next-generation sequencing allows for the sequencing of the entire genome of a …
Mayo scientists researching 'beyond DNA' to advance …
2021年4月22日 · Advances in DNA sequencing have also provided infectious diseases diagnostics. With the advent of capillary sequencers in the 1990s, identification of cultured bacteria with 16S ribosomal RNA gene polymerase chain reaction/Sanger sequencing was adopted into clinical practice at Mayo Clinic.
New Mayo Clinic GeneGuide DNA testing application provides …
2018年10月1日 · ROCHESTER, Minn. — Mayo Clinic released a new DNA product with Helix, a personal genomics company, called "Mayo Clinic GeneGuide." The DNA-powered product provides healthy individuals with genetic testing and insights with a focus on education. This product is backed by Mayo medical science and expertise. “The Mayo Clinic GeneGuide app uses the highest quality […]
Mayo Clinic to sequence 100K participants to build genomic …
2020年1月9日 · ROCHESTER, Minn. — Mayo Clinic is creating a library of genomic sequencing data on 100,000 consented Mayo Clinic participants to advance research and patient care. “We believe that whole exome sequencing has the potential to reveal predispositions to health problems and enable earlier use of preventive measures throughout a person’s lifespan,” says Keith Stewart, M.B., […]
Genomics study enrolls 100,000 participants - Mayo Clinic News …
2024年3月7日 · The Tapestry DNA Sequencing Research Study — a massive, decentralized clinical research study, aimed to complete exome sequencing of 100,000 Mayo patients and return the results to their electronic health records for three hereditary conditions: familial hypercholesterolemia — a form of high cholesterol; hereditary breast and ovarian cancer ...
Tomorrow’s Cure: How DNA guides cancer detection
2024年7月10日 · This week's podcast episode of Tomorrow's Cure explores how DNA could be used to detect blood cancers before they ever develop. Episode experts include Dr. Mrinal Patnaik , a hematologist, internist and oncologist at Mayo Clinic; and Dr. Kelly Bolton , an oncologist at Washington University in St. Louis.
Mayo Clinic researchers pinpoint genetic variations that might …
2022年7月25日 · ROCHESTER, Minn. — Researchers at Mayo Clinic's Center for Individualized Medicine have discovered key human genomic signatures that could help explain why COVID-19 is severe in some people and mild in others. After analyzing volumes of diverse worldwide DNA sequence data, the scientists identified mutations in two …
Mayo Clinic's largest-ever exome study offers blueprint for …
2024年12月3日 · Participants' saliva samples from all three of Mayo Clinic's campuses — in Minnesota, Arizona and Florida — were used to extract DNA for exome sequencing. Exome sequencing analyzes nearly 20,000 genes that provide instructions for making proteins, which play many critical roles in the body.